Klion, Amy D., M.D.
individual record
Investigator
Positions:
- Investigator, Human Eosinophil Section
Research Areas:
Research & Experimental Medicine,
Education & Educational Research,
Rheumatology,
Biochemistry & Molecular Biology,
Tropical Medicine,
Pharmacology & Pharmacy,
Infectious Diseases,
Microbiology,
Public, Environmental & Occupational Health,
Dermatology,
Hematology,
Immunology,
Allergy,
Parasitology,
Toxicology
Research Areas:
Research & Experimental Medicine,
Education & Educational Research,
Rheumatology,
Biochemistry & Molecular Biology,
Tropical Medicine,
Pharmacology & Pharmacy,
Infectious Diseases,
Microbiology,
Public, Environmental & Occupational Health,
Dermatology,
Hematology,
Immunology,
Allergy,
Parasitology,
Toxicology
overview
Dr. Klion earned her B.A. from Princeton University and her M.D. from New York University School of Medicine. After completing a residency in internal medicine at Johns Hopkins University, she was a postdoctoral fellow in the Laboratory of Parasitic Diseases from 1989 to 1991. She completed her fellowship in infectious diseases at the University of Iowa Hospitals and Clinics in Iowa City, IA, where she was appointed an assistant professor in the division of infectious diseases prior to returning to the Laboratory of Parasitic Diseases in 1997 as a staff clinician. She became a tenure-track clinical investigator in the Laboratory of Parasitic Diseases in 2009 and a senior clinical investigator in 2014.
selected publications
Articles3
- (2014). Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 133(4), 1149-1161.
- (2012). Expansion of somatically reverted memory CD8(+) T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus. JOURNAL OF EXPERIMENTAL MEDICINE. 209(5), 911-922.
- (2006). Selective generation of functional somatically mutated IgM(+)CD27(+), but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease. JOURNAL OF CLINICAL INVESTIGATION. 116(2), 322-333.
Academic Articles138
- (2020). Single-Organ and Multisystem Hypereosinophilic Syndrome Patients with Gastrointestinal Manifestations Share Common Characteristics. Journal of Allergy and Clinical Immunology-In Practice. 8(8), 2718-+.
- (2020). A new dawn for eosinophils in the tumour microenvironment. NATURE REVIEWS CANCER. 20(10), 594-607.
- (2020). Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features. AMERICAN JOURNAL OF PATHOLOGY. 190(7), 1438-1448.
- (2020). Platelet-derived growth factor receptor-alpha-positive myeloid neoplasm presenting as eosinophilic gastrointestinal disease. Journal of Allergy and Clinical Immunology-In Practice. 8(6), 2089-2091.
- (2020). A Test-and-Not-Treat Strategy for Onchocerciasis Elimination in Loa loa-coendemic Areas: Cost Analysis of a Pilot in the Soa Health District, Cameroon. CLINICAL INFECTIOUS DISEASES. 70(8), 1628-1635.
Research Areas:
Research & Experimental Medicine,
Education & Educational Research,
Rheumatology,
Biochemistry & Molecular Biology,
Tropical Medicine,
Pharmacology & Pharmacy,
Infectious Diseases,
Microbiology,
Public, Environmental & Occupational Health,
Dermatology,
Hematology,
Immunology,
Allergy,
Parasitology,
Toxicology
Research Areas:
Research & Experimental Medicine,
Education & Educational Research,
Rheumatology,
Biochemistry & Molecular Biology,
Tropical Medicine,
Pharmacology & Pharmacy,
Infectious Diseases,
Microbiology,
Public, Environmental & Occupational Health,
Dermatology,
Hematology,
Immunology,
Allergy,
Parasitology,
Toxicology