Bhandoola, Avinash, Ph.D.
individual record
Senior Investigator
Positions:
- Senior Investigator, Laboratory of Genome Integrity
overview
Avinash Bhandoola received a Ph.D. from the University of Pennsylvania in 1994, and did a postdoctoral fellowship with Dr. Alfred Singer at NCI focused on the rules underlying lineage choice. He joined the faculty of the University of Pennsylvania in 2001, received tenure in 2007, and was promoted to full professor in 2012. He subsequently joined the Laboratory of Genome Integrity in 2014.
selected publications
Academic Articles110
- (2020). A Shared Regulatory Element Controls the Initiation of Tcf7 Expression During Early T Cell and Innate Lymphoid Cell Developments. Frontiers in Immunology. 11,
- (2020). Single-cell analysis of ROR alpha tracer mouse lung reveals ILC progenitors and effector ILC2 subsets. JOURNAL OF EXPERIMENTAL MEDICINE. 217(3),
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- (2019). Blocked O-GlcNAc cycling disrupts mouse hematopoeitic stem cell maintenance and early T cell development. Scientific Reports. 9,
- (2019). Cutting Edge: Core Binding Factor beta Is Required for Group 2 Innate Lymphoid Cell Activation. JOURNAL OF IMMUNOLOGY. 202(6), 1669-1673.
- (2019). Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects. BLOOD. 133(18), 1977-1988.
- (2019). Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. AMERICAN JOURNAL OF HUMAN GENETICS. 105(3), 549-561.
- (2019). Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells. JOURNAL OF IMMUNOLOGY. 203(3), 686-695.
- (2019). MAIT cells are imprinted by the microbiota in early life and promote tissue repair. SCIENCE. 366(6464), 445-+.