Clarivate VIVO Sandbox

Academic Articles110

• (2020). Postnatal Involution and Counter-Involution of the Thymus. Frontiers in Immunology. 11,

  
• (2020). A Shared Regulatory Element Controls the Initiation of Tcf7 Expression During Early T Cell and Innate Lymphoid Cell Developments. Frontiers in Immunology. 11,

  
• (2020). Single-cell analysis of ROR alpha tracer mouse lung reveals ILC progenitors and effector ILC2 subsets. JOURNAL OF EXPERIMENTAL MEDICINE. 217(3),

  
• (2020). Switch hitter: Bcl11b in T cells and ILC2s. JOURNAL OF EXPERIMENTAL MEDICINE. 217(1),

  
• (2019). Blocked O-GlcNAc cycling disrupts mouse hematopoeitic stem cell maintenance and early T cell development. Scientific Reports. 9,

  
• (2019). Cutting Edge: Core Binding Factor beta Is Required for Group 2 Innate Lymphoid Cell Activation. JOURNAL OF IMMUNOLOGY. 202(6), 1669-1673.

  
• (2019). Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects. BLOOD. 133(18), 1977-1988.

  
• (2019). Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. AMERICAN JOURNAL OF HUMAN GENETICS. 105(3), 549-561.

  
• (2019). Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells. JOURNAL OF IMMUNOLOGY. 203(3), 686-695.

  
• (2019). MAIT cells are imprinted by the microbiota in early life and promote tissue repair. SCIENCE. 366(6464), 445-+.

  
• (2019). Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth. Nature Communications. 10,

  
• (2019). Response to Comment on "Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells". JOURNAL OF IMMUNOLOGY. 203(9), 2355-2356.

  
• (2019). TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8(+) T cell exhaustion. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 116(25), 12410-12415.

  
• (2019). The PLOS Biology XV Collection: 15 Years of Exceptional Science Highlighted across 12 Months. 17(2),

  
• (2019). The transcription factor c-Myb regulates CD8(+) T cell stemness and antitumor immunity. NATURE IMMUNOLOGY. 20(3), 337-+.

  
• (2018). Development and differentiation of early innate lymphoid progenitors. JOURNAL OF EXPERIMENTAL MEDICINE. 215(1), 249-262.

  
• (2018). Lineage specification in innate lymphocytes. CYTOKINE & GROWTH FACTOR REVIEWS. 42, 20-26.

  
• (2018). Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells. IMMUNITY. 48(2), 243-+.

  
• (2017). CD4(+) T cell effector commitment coupled to self-renewal by asymmetric cell divisions. JOURNAL OF EXPERIMENTAL MEDICINE. 214(1), 39-47.

  
• (2017). Cutting Edge: Notch Signaling Promotes the Plasticity of Group-2 Innate Lymphoid Cells. JOURNAL OF IMMUNOLOGY. 198(5), 1798-1803.

  
• (2017). T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction. JCI Insight. 2(10),

  
• (2016). A doppelganger of T cell development. CELL CYCLE. 15(4), 479-480.

  
• (2016). CD8(+) T Lymphocyte Self-Renewal during Effector Cell Determination. Cell Reports. 17(7), 1773-1782.

  
• (2016). Coreceptor Reversal in the Thymus: Signaled CD4(+)8(+) Thymocytes Initially Terminate CD8 Transcription Even When Differentiating into CD8(+) T Cells. JOURNAL OF IMMUNOLOGY. 196(5), 1985-1997.
• (2016). Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 137(2), 571-578.

  
• (2016). Intrathymic Injection. 1323, 203-209.

  
• (2016). Progress on thymic function from Maui. NATURE IMMUNOLOGY. 17(10), 1129-1132.

  
• (2016). Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML. Science Signaling. 9(445),

  
• (2016). The development of adult innate lymphoid cells. CURRENT OPINION IN IMMUNOLOGY. 39, 114-120.

  
• (2015). Editorial: Ephs, ephrins, and early T cell development. JOURNAL OF LEUKOCYTE BIOLOGY. 98(6), 877-879.

  
• (2015). TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow. NATURE IMMUNOLOGY. 16(10), 1044-+.

  
• (2015). Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells. IMMUNITY. 43(2), 354-368.

  
• (2015). Transcriptional Regulation of Innate and Adaptive Lymphocyte Lineages. Annual Review of Immunology. 33, 607-642.

  
• (2014). Adaptation of Innate Lymphoid Cells to a Micronutrient Deficiency Promotes Type 2 Barrier Immunity. SCIENCE. 343(6169), 432-437.

  
• (2014). Chemokine treatment rescues profound T-lineage progenitor homing defect after bone marrow transplant conditioning in mice. BLOOD. 124(2), 296-304.

  
• (2014). The microRNA Biogenesis Machinery Modulates Lineage Commitment during alpha beta T Cell Development. JOURNAL OF IMMUNOLOGY. 193(8), 4032-4042.

  
• (2014). Trafficking to the Thymus. Current Topics in Microbiology and Immunology. 373, 87-111.

  
• (2013). Deconstructing development. NATURE IMMUNOLOGY. 14(6), 529-531.

  
• (2013). Early T-cell progenitors are the major granulocyte precursors in the adult mouse thymus. BLOOD. 121(1), 64-71.

  
• (2013). IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. JOURNAL OF EXPERIMENTAL MEDICINE. 210(9), 1823-1837.

  
• (2013). T Cell Factor 1 Is Required for Group 2 Innate Lymphoid Cell Generation. IMMUNITY. 38(4), 694-704.

  
• (2013). T cell development requires constraint of the myeloid regulator C/EBP-alpha by the Notch target and transcriptional repressor Hes1. NATURE IMMUNOLOGY. 14(12), 1277-+.

  
• (2012). Expression of Functional P-Selectin Glycoprotein Ligand 1 on Hematopoietic Progenitors Is Developmentally Regulated. JOURNAL OF IMMUNOLOGY. 188(9), 4385-4393.

  
• (2012). HEMATOPOIESIS & STEM CELLS Decoding HSC heterogeneity. BLOOD. 119(21), 4819-4820.

  
• (2012). Losing TREC with Age. IMMUNITY. 36(2), 163-165.

  
• (2012). Rebuilding the Thymus. SCIENCE. 336(6077), 40-41.

  
• (2011). A critical role for TCF-1 in T-lineage specification and differentiation. NATURE. 476(7358), 63-+.

  
• (2011). Cutting Edge: Natural Helper Cells Derive from Lymphoid Progenitors. JOURNAL OF IMMUNOLOGY. 187(11), 5505-5509.

  
• (2011). Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation. BLOOD. 118(7), 1962-1970.

  
• (2011). Erythroid/Myeloid Progenitors and Hematopoietic Stem Cells Originate from Distinct Populations of Endothelial Cells. Cell Stem Cell. 9(6), 541-552.

  
• (2011). Hematopoietic progenitor migration to the adult thymus. Annals of the New York Academy of Sciences. 1217, 122-138.

  
• (2011). Identification of Flt3(+)CD150(-) myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential. BLOOD. 118(10), 2723-2732.

  
• (2011). Patients on HAART often have an excess of unintegrated HIV DNA: Implications for monitoring reservoirs. VIROLOGY. 409(1), 46-53.

  
• (2011). Signal integration and crosstalk during thymocyte migration and emigration. NATURE REVIEWS IMMUNOLOGY. 11(7), 469-477.

  
• (2011). T Cell Development Critically Depends on Prethymic Stromal Patched Expression. JOURNAL OF IMMUNOLOGY. 186(6), 3383-3391.

  
• (2010). CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus. BLOOD. 115(10), 1897-1905.

  
• (2010). Eliciting the T cell fate with Notch. SEMINARS IN IMMUNOLOGY. 22(5), 254-260.

  
• (2010). Ezrin Is Highly Expressed in Early Thymocytes, but Dispensable for T Cell Development in Mice. PLoS One. 5(8),

  
• (2010). Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development. BLOOD. 115(3), 510-518.

  
• (2010). IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses. NATURE. 464(7293), 1362-U8.

  
• (2010). Notch dimerization is required for leukemogenesis and T-cell development. GENES & DEVELOPMENT. 24(21), 2395-2407.

  
• (2010). T-cell lineage determination. IMMUNOLOGICAL REVIEWS. 238, 12-22.

  
• (2010). There's many a CLP on the path to B. BLOOD. 115(13), 2562-2563.

  
• (2009). Complement-dependent T-cell lymphopenia caused by thymocyte deletion of the membrane complement regulator Crry. BLOOD. 113(12), 2684-2694.

  
• (2009). Untangling the T branch of the hematopoiesis tree. CURRENT OPINION IN IMMUNOLOGY. 21(2), 121-126.

  
• (2008). Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. Cell Stem Cell. 2(4), 356-366.

  
• (2008). Immunology at the University of Pennsylvania. IMMUNOLOGIC RESEARCH. 42(1-3), 1-2.

  
• (2008). Progenitor migration to the thymus and T cell lineage commitment. IMMUNOLOGIC RESEARCH. 42(1-3), 65-74.

  
• (2008). Putting ThPOK in place. NATURE IMMUNOLOGY. 9(10), 1095-1097.

  
• (2008). The earliest thymic progenitors for T cells possess myeloid lineage potential. NATURE. 452(7188), 764-U9.

  
• (2008). The long road to the thymus: the generation, mobilization, and circulation of T-cell progenitors in mouse and man. Seminars in Immunopathology. 30(4), 371-382.

  
• (2007). Commitment and developmental potential of extrathymic and intrathymic T cell precursors: Plenty to choose from. IMMUNITY. 26(6), 678-689.

  
• (2007). Deletion of the developmentallv essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell. 1(1), 113-126.

  
• (2007). Multiple prethymic defects underlie age-related loss of T progenitor competence. BLOOD. 110(4), 1161-1167.

  
• (2007). Selective thymus settling regulated by cytokine and chemokine receptors. JOURNAL OF IMMUNOLOGY. 178(4), 2008-2017.

  
• (2006). From stem cell to T cell: one route or many?. NATURE REVIEWS IMMUNOLOGY. 6(2), 117-126.

  
• (2006). Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation. BLOOD. 107(9), 3511-3519.

  
• (2006). Sialylation regulates peripheral tolerance in CD4+T cells. INTERNATIONAL IMMUNOLOGY. 18(5), 627-635.

  
• (2006). Stat5a/b are essential for normal lymphoid development and differentiation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 103(4), 1000-1005.

  
• (2006). The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. JOURNAL OF EXPERIMENTAL MEDICINE. 203(10), 2239-2245.

  
• (2006). Trafficking from the bone marrow to the thymus: a prerequisite for thymopoiesis. IMMUNOLOGICAL REVIEWS. 209, 47-57.

  
• (2005). Aging and T cell development: Interplay between progenitors and their environment. SEMINARS IN IMMUNOLOGY. 17(5), 337-346.

  
• (2005). Closer to the source: Notch and the nature of thymus-settling cells. IMMUNITY. 23(3), 245-248.

  
• (2005). Notch signaling controls the generation and differentiation of early T lineage progenitors. NATURE IMMUNOLOGY. 6(7), 663-670.

  
• (2004). Circulating hematopoietic progenitors with T lineage potential. NATURE IMMUNOLOGY. 5(9), 953-960.

  
• (2003). CD4(+) T-cell responses to self-peptide-MHC. TRENDS IN IMMUNOLOGY. 24(4), 171-171.

  
• (2003). Early T lineage progenitors: New insights, but old questions remain. JOURNAL OF IMMUNOLOGY. 171(11), 5653-5658.

  
• (2003). In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8(+) T cells. JOURNAL OF EXPERIMENTAL MEDICINE. 197(4), 475-487.

  
• (2003). Thymopoiesis independent of common lymphoid progenitors. NATURE IMMUNOLOGY. 4(2), 168-174.

  
• (2002). CD5-mediated inhibition of TCR signaling during intrathymic selection and development does not require the CD5 extracellular domain. EUROPEAN JOURNAL OF IMMUNOLOGY. 32(6), 1811-1817.
• (2002). Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: Evidence from a lymphopenic T cell model. IMMUNITY. 17(4), 425-436.

  
• (2002). The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7. JOURNAL OF EXPERIMENTAL MEDICINE. 196(5), 705-711.

  
• (2000). CD8 coreceptor extinction in signaled CD4(+) CD8(+) thymocytes: Coordinate roles for both transcriptional and posttranscriptional regulatory mechanisms in developing thymocytes. MOLECULAR AND CELLULAR BIOLOGY. 20(11), 3852-3859.

  
• (2000). Coreceptor reversal in the thymus: Signaled CD4(+)8(+) thymocytes initially terminate CD8 transcription even when differentiating into CD8(+) T cells. IMMUNITY. 13(1), 59-71.

  
• (2000). Immature thymocytes undergoing receptor rearrangements are resistant to an Atm-dependent death pathway activated in mature T cells by double-stranded DNA breaks. JOURNAL OF EXPERIMENTAL MEDICINE. 192(6), 891-897.

  
• (2000). Programming for cytotoxic effector function occurs concomitantly with CD4 extinction during CD8(+) T cell differentiation in the thymus. INTERNATIONAL IMMUNOLOGY. 12(7), 1035-1040.

  
• (2000). Response to RAG-mediated V(D)J cleavage by NBS1 and gamma-H2AX. SCIENCE. 290(5498), 1962-1964.

  
• (1999). Positive selection as a developmental progression initiated by alpha beta TCR signals that fix TCR specificity prior to lineage commitment. IMMUNITY. 10(3), 301-311.

  
• (1999). Signals involved in CD4/CD8 lineage commitment: Current concepts and potential mechanisms. SEMINARS IN IMMUNOLOGY. 11(4), 273-281.

  
• (1998). Functional and physical association of a cell surface phospholipid and interleukin-2 receptor p55(alpha) subunits. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 1414(1-2), 51-64.