- Senior Investigator, Molecular Hematopoiesis Section
Cynthia Dunbar earned a B.A. magna cum laude in the history of science from Harvard University in 1980 and a M.D. magna cum laude from Harvard Medical School in 1984. She subsequently completed her internal medicine internship and residency at Boston City Hospital and hematology fellowship training at the University of California, San Francisco. She came to the NHLBI as a postdoctoral fellow in the laboratory of Arthur Nienhuis in 1987, became an Investigator in 1993, and has been Head of the Molecular Hematopoiesis Section since 2000. Dr. Dunbar has received numerous awards for teaching, mentorship, and research, including the NIH Clinical Center Distinguished Clinical Teacher Award, the John Decker Memorial Lectureship, and the Brigham and Women's Hospital Moloney Award and Lectureship. She has authored more than 200 peer-reviewed scientific and review articles, and has given numerous invited lectures and presentations about her work. Dr. Dunbar is the Editor-in-Chief of the journal Blood, the flagship publication of the American Society of Hematology. She is also a member of the American Society for Clinical Investigation, a Master of the American College of Physicians, a founder and board member of the American Society for Cell and Gene Therapy, and served seventeen years as the director of the NIH Hematology Clinical Fellowship training program.
- (2020). Clonal tracking of erythropoiesis in rhesus macaques. HAEMATOLOGICA. 105(7), 1813-1824.
- (2020). Immunosuppression and growth factors for severe aplastic anemia: new data for old questions. HAEMATOLOGICA. 105(5), 1170-1171.
- (2019). Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque. MOLECULAR THERAPY. 27(6), 1074-1086.
- (2019). Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model. MOLECULAR THERAPY. 27(9), 1586-1596.
- (2019). CRISPR/Cas9 PIG-A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs. BLOOD. 133(23), 2542-2545.
- (2019). Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-gamma. BLOOD. 133(19), 2043-2055.
- (2019). Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naive Rhesus Macaques. Frontiers in Immunology. 10,
- (2019). Telomere dynamics and hematopoietic differentiation of human DKC1-mutant induced pluripotent stem cells. Stem Cell Research. 40,
- (2019). Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag. BLOOD. 133(24), 2575-2585.
- (2018). An Introduction to the Analysis of Single-Cell RNA-Sequencing Data. Molecular Therapy-Methods & Clinical Development.