- Senior Investigator, Molecular Structure Section
Dr. Berger earned his B.S. in chemistry from City College of the City University of New York in 1968. He received his Ph.D. in biochemistry and molecular biology in 1973 from Cornell University. He went on to do a postdoctoral fellowship in the department of genetics, biochemistry, and neurobiology at Stanford University School of Medicine from 1973 to 1976 and another fellowship in the department of cellular and developmental immunology at Scripps Clinical and Research Foundation from 1976 to 1977. He was a staff scientist with the Cell Biology Group at the Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts, from 1977 to 1987. He joined the NIAID Laboratory of Viral Diseases in 1987 and became chief of the Molecular Structure Section in 1995.
American Academy of Microbiology Fellow; Bernard Fields Memorial Lectureship, CROI 2007;1st NIH World AIDS Day Award 2006; ISI Highly Cited Researcher, Breakthrough of the Year, Science 1996; AAAS-Newcomb Cleveland Prize 1997; Great Experiments; Kenneth Fong/Clontech Award; Novartis-Drew Award for Biomedical Science; Damon Runyon-Walter Winchell Foundation Most Prominent Alumni; AMA/NIAID Nathan Davis Award; NIH Outstanding Contributions to Education of Postbaccalaureate Trainees; Norman P Salzman Memorial Mentor Award in Virology, Honorable Mention
National Institutes of Health Interest Group Memberships
Virology Interest Group, Immunology Interest Group, Antibody Interest Group, Viral Hepatitis Interest Group
- (1988). A SOLUBLE RECOMBINANT POLYPEPTIDE COMPRISING THE AMINO-TERMINAL HALF OF THE EXTRACELLULAR REGION OF THE CD4-MOLECULE CONTAINS AN ACTIVE BINDING-SITE FOR HUMAN IMMUNODEFICIENCY VIRUS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 85(7), 2357-2361.
- (1988). BINDING REGION FOR HUMAN IMMUNODEFICIENCY VIRUS (HIV) AND EPITOPES FOR HIV-BLOCKING MONOCLONAL-ANTIBODIES OF THE CD4 MOLECULE DEFINED BY SITE-DIRECTED MUTAGENESIS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 85(23), 9273-9277.
- (1988). SELECTIVE KILLING OF HIV-INFECTED CELLS BY RECOMBINANT HUMAN CD4-PSEUDOMONAS EXOTOXIN HYBRID PROTEIN. NATURE. 335(6188), 369-372.