- Senior Investigator, Clinical Trial Branch
Emily Chew is the Deputy Director of the Division of Epidemiology and Clinical Applications (DECA), at the National Eye Institute. She is also the Chief of the Clinical Trials Branch in the division. Emily received her medical degree and her ophthalmology training at the U. of Toronto, Canada. She completed her fellowship in medical retina at the Wilmer Eye Institute, the Johns Hopkins Medical Institutes and the U. of Nijmegen, the Netherlands.
Her research interest includes phase I/II clinical trials and epidemiologic studies in retinovascular diseases such as age-related macular degeneration, diabetic retinopathy, and other ocular diseases. She has worked extensively in large multi-centered trials headed by the staff from her division, including the Early Treatment Diabetic Retinopathy Study (ETDRS), the Age-Related Eye Disease Study (AREDS) and the Age-Related Eye Disease Study 2 (AREDS2), which she chairs. She works on other clinical trials in collaboration with other institutes within NIH such as the Actions to Control Cardiovascular Risk in Diabetes (ACCORD) Trial and she chairs the ACCORD Eye Study. She directs the clinical portion of the international study, Macular Telangiectasia Project.
- (2014). Effect of Long-Chain omega-3 Fatty Acids and Lutein plus Zeaxanthin Supplements on Cardiovascular Outcomes Results of the Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial. JAMA Internal Medicine. 174(5), 763-771.
- (2014). Visual Acuity after Cataract Surgery in Patients with Age-Related Macular Degeneration. OPHTHALMOLOGY. 121(6), 1229-1236.
- (2020). Incidence of Macular Atrophy after Untreated Neovascular Age-Related Macular Degeneration Age-Related Eye Disease Study Report 40. OPHTHALMOLOGY. 127(6), 784-792.
- (2020). Re: Van Asten et al.: No CFH/ARMS2 interaction with omega-3 fatty acids, low vs high zinc, or beta-carotene versus Lutein and Zeaxanthin on progression of age-related macular degeneration in the Age-Related Eye Disease Study 2: Age-Related Eye Disease Study 2 Report No. 18 REPLY. OPHTHALMOLOGY. 127(3), E19-E20.
- (2020). Vascular Changes in the Retina and Choroid of Patients With EPAS1 Gain-of-Function Mutation Syndrome. JAMA Ophthalmology. 138(2), 148-155.
- (2019). Age-related changes of the retinal microvasculature. PLoS One. 14(5),
- (2019). Association of Dietary and Supplementary Calcium Intake With Age-Related Macular Degeneration Age-Related Eye Disease Study Report 39. JAMA Ophthalmology. 137(5), 543-550.