Burgess, Harold A., Ph.D.
individual record
Investigator
Positions:
- Investigator, Unit on Behavioral Neurogenetics
overview
Dr. Harold Burgess received his B.S. from the University of Melbourne, Australia and his Ph.D. from the Weizmann Institute of Science, Israel studying molecular interactions underlying cortical development. He did postdoctoral training with Dr. Michael Granato at the University of Pennsylvania, where he developed computational tools for high throughput analysis of behavior in larval zebrafish. Dr. Burgess joined NICHD as an investigator in 2008. His laboratory now combines genetic and imaging techniques to study neural circuits required for sensory guided behavior in zebrafish.
selected publications
Articles2
- (2020). A Model to Study NMDA Receptors in Early Nervous System Development. JOURNAL OF NEUROSCIENCE. 40(18), 3631-3645.
Academic Articles42
- (2020). A Model to Study NMDA Receptors in Early Nervous System Development. JOURNAL OF NEUROSCIENCE. 40(18), 3631-3645.
- (2020). Molecular and cellular determinants of motor asymmetry in zebrafish. Nature Communications. 11(1),
- (2019). Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System. CURRENT BIOLOGY. 29(12), 2009-+.
- (2018). Morphometric analysis and neuroanatomical mapping of the zebrafish brain. METHODS. 150, 49-62.
- (2018). Presynaptic Inhibition Selectively Gates Auditory Transmission to the Brainstem Startle Circuit. CURRENT BIOLOGY. 28(16), 2527-+.
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- (2017). High-precision registration between zebrafish brain atlases using symmetric diffeomorphic normalization. GigaScience. 6(8),
- (2017). Search strategy is regulated by somatostatin signaling and deep brain photoreceptors in zebrafish. BMC BIOLOGY. 15,
- (2016). Genetically Blocking the Zebrafish Pineal Clock Affects Circadian Behavior. PLoS Genetics. 12(11),
- (2016). Motivated state control in larval zebrafish: behavioral paradigms and anatomical substrates. JOURNAL OF NEUROGENETICS. 30(2), 122-132.
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- (2015). A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies. Frontiers in Neural Circuits. 9,
- (2015). Gsx1 expression defines neurons required for prepulse inhibition. MOLECULAR PSYCHIATRY. 20(8), 974-985.
- (2015). Increased functional protein expression using nucleotide sequence features enriched in highly expressed genes in zebrafish. NUCLEIC ACIDS RESEARCH. 43(7),
- (2014). Direct activation of the Mauthner cell by electric field pulses drives ultrarapid escape responses. JOURNAL OF NEUROPHYSIOLOGY. 112(4), 834-844.
- (2014). Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure. Disease Models & Mechanisms. 7(2), 289-298.
- (2013). Enlightening the brain: Linking deep brain photoreception with behavior and physiology. BIOESSAYS. 35(9), 775-779.
- (2013). Habenular commissure formation in zebrafish is regulated by the pineal gland-specific gene unc119c. DEVELOPMENTAL DYNAMICS. 242(9), 1033-1042.
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- (2012). Brain selective transgene expression in zebrafish using an NRSE derived motif. Frontiers in Neural Circuits. 6,
- (2012). Deep Brain Photoreceptors Control Light-Seeking Behavior in Zebrafish Larvae. CURRENT BIOLOGY. 22(21), 2042-2047.
- (2012). Mutations in vacuolar H+-ATPase subunits lead to biliary developmental defects in zebrafish. DEVELOPMENTAL BIOLOGY. 365(2), 434-444.
- (2012). The Dorsal Raphe Modulates Sensory Responsiveness during Arousal in Zebrafish. JOURNAL OF NEUROSCIENCE. 32(43), 15205-15215.
- (2011). Molecular-Genetic Mapping of Zebrafish Mutants with Variable Phenotypic Penetrance. PLoS One. 6(10),
- (2010). A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3. DEVELOPMENT. 137(15), 2587-2596.
- (2010). Distinct Retinal Pathways Drive Spatial Orientation Behaviors in Zebrafish Navigation. CURRENT BIOLOGY. 20(4), 381-386.
- (2009). Determining the function of zebrafish epithalamic asymmetry. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 364(1519), 1021-1032.
- (2009). Tbx2b is required for ultraviolet photoreceptor cell specification during zebrafish retinal development. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 106(6), 2023-2028.
- (2009). Unidirectional startle responses and disrupted left-right co-ordination of motor behaviors in robo3 mutant zebrafish. GENES BRAIN AND BEHAVIOR. 8(5), 500-511.
- (2007). Modulation of locomotor activity in larval zebrafish during light adaptation. JOURNAL OF EXPERIMENTAL BIOLOGY. 210(14), 2526-2539.
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- (2002). Alternative splice variants of doublecortin-like kinase are differentially expressed and have different kinase activities. JOURNAL OF BIOLOGICAL CHEMISTRY. 277(20), 17696-17705.
- (2001). Cleavage of doublecortin-like kinase by calpain releases an active kinase fragment from a microtubule anchorage domain. JOURNAL OF BIOLOGICAL CHEMISTRY. 276(39), 36397-36403.
- (2000). Doublecortin mutations cluster in evolutionarily conserved functional domains. HUMAN MOLECULAR GENETICS. 9(5), 703-712.
- (2000). Doublecortin-like kinase is associated with microtubules in neuronal growth cones. MOLECULAR AND CELLULAR NEUROSCIENCE. 16(5), 529-541.
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- (1999). KIAA0369, doublecortin-like kinase, is expressed during brain development. JOURNAL OF NEUROSCIENCE RESEARCH. 58(4), 567-575.