Pastan, Ira, M.D.
individual record
NIH Distinguished Investigator
Positions:
- NIH Distinguished Investigator, Laboratory of Molecular Biology
Research Areas:
Research & Experimental Medicine,
Engineering,
Genetics & Heredity,
Food Science & Technology,
Rheumatology,
Science & Technology - Other Topics,
Cardiovascular System & Cardiology,
Biophysics,
Pharmacology & Pharmacy,
Radiology, Nuclear Medicine & Medical Imaging,
Pediatrics,
Anatomy & Morphology,
Reproductive Biology,
Endocrinology & Metabolism,
Biochemistry & Molecular Biology,
Oncology,
Materials Science,
Microbiology,
Respiratory System,
Cell Biology,
Chemistry,
Obstetrics & Gynecology,
Hematology,
Biotechnology & Applied Microbiology,
Transplantation,
Urology & Nephrology,
Physiology,
Immunology,
Neurosciences & Neurology,
Virology,
Medical Laboratory Technology,
Parasitology,
Pathology,
Toxicology
Research Areas:
Research & Experimental Medicine,
Engineering,
Genetics & Heredity,
Food Science & Technology,
Rheumatology,
Science & Technology - Other Topics,
Cardiovascular System & Cardiology,
Biophysics,
Pharmacology & Pharmacy,
Radiology, Nuclear Medicine & Medical Imaging,
Pediatrics,
Anatomy & Morphology,
Reproductive Biology,
Endocrinology & Metabolism,
Biochemistry & Molecular Biology,
Oncology,
Materials Science,
Microbiology,
Respiratory System,
Cell Biology,
Chemistry,
Obstetrics & Gynecology,
Hematology,
Biotechnology & Applied Microbiology,
Transplantation,
Urology & Nephrology,
Physiology,
Immunology,
Neurosciences & Neurology,
Virology,
Medical Laboratory Technology,
Parasitology,
Pathology,
Toxicology
selected publications
Articles1
- (2020). Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti-PD-1 antibody in patients with mesothelioma and mouse tumor models. Science Translational Medicine. 12(550),
Academic Articles1201
- (2020). Phase 1 study of the immunotoxin LMB-100 in patients with mesothelioma and other solid tumors expressing mesothelin. CANCER. 126(22), 4936-4947.
- (2020). Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti-PD-1 antibody in patients with mesothelioma and mouse tumor models. Science Translational Medicine. 12(550),
- (2020). Population pharmacokinetics, efficacy, and safety of moxetumomab pasudotox in patients with relapsed or refractory hairy cell leukaemia. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 86(7), 1367-1376.
- (2020). Phase I/II Study of the Mesothelin-targeted Immunotoxin LMB-100 with Nab-Paclitaxel for Patients with Advanced Pancreatic Adenocarcinoma. CLINICAL CANCER RESEARCH. 26(4), 828-836.
Research Areas:
Research & Experimental Medicine,
Engineering,
Genetics & Heredity,
Food Science & Technology,
Rheumatology,
Science & Technology - Other Topics,
Cardiovascular System & Cardiology,
Biophysics,
Pharmacology & Pharmacy,
Radiology, Nuclear Medicine & Medical Imaging,
Pediatrics,
Anatomy & Morphology,
Reproductive Biology,
Endocrinology & Metabolism,
Biochemistry & Molecular Biology,
Oncology,
Materials Science,
Microbiology,
Respiratory System,
Cell Biology,
Chemistry,
Obstetrics & Gynecology,
Hematology,
Biotechnology & Applied Microbiology,
Transplantation,
Urology & Nephrology,
Physiology,
Immunology,
Neurosciences & Neurology,
Virology,
Medical Laboratory Technology,
Parasitology,
Pathology,
Toxicology
Research Areas:
Research & Experimental Medicine,
Engineering,
Genetics & Heredity,
Food Science & Technology,
Rheumatology,
Science & Technology - Other Topics,
Cardiovascular System & Cardiology,
Biophysics,
Pharmacology & Pharmacy,
Radiology, Nuclear Medicine & Medical Imaging,
Pediatrics,
Anatomy & Morphology,
Reproductive Biology,
Endocrinology & Metabolism,
Biochemistry & Molecular Biology,
Oncology,
Materials Science,
Microbiology,
Respiratory System,
Cell Biology,
Chemistry,
Obstetrics & Gynecology,
Hematology,
Biotechnology & Applied Microbiology,
Transplantation,
Urology & Nephrology,
Physiology,
Immunology,
Neurosciences & Neurology,
Virology,
Medical Laboratory Technology,
Parasitology,
Pathology,
Toxicology