Oppenheim, Joost J., M.D.
individual record
Senior Investigator
Positions:
- Senior Investigator, Cancer and Inflammation Program
Research Areas:
Research & Experimental Medicine,
Engineering,
Science & Technology - Other Topics,
Oncology,
Biochemistry & Molecular Biology,
Materials Science,
Biophysics,
Pharmacology & Pharmacy,
Infectious Diseases,
Cell Biology,
Chemistry,
Hematology,
Life Sciences & Biomedicine - Other Topics,
Immunology
Research Areas:
overview
Dr. Oppenheim obtained his M.D. degree from the Columbia College of Physicians and Surgeons, New York, trained as a clinical associate at the National Cancer Institute (NCI), Bethesda, Maryland, and was a postdoctoral fellow at the University of Birmingham, England, in immunology. He returned to the National Institute of Dental Research and subsequently headed the Section of Cellular Immunology there and, since 1983, has been head of the Laboratory of Molecular Immunoregulation, NCI-Frederick.
selected publications
Academic Articles457
- (2016). IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. JOURNAL OF EXPERIMENTAL MEDICINE. 213(10), 2147-2166.
- (2016). Paradoxical effects of targeting TNF signalling in the treatment of autoimmunity. Nature Reviews Rheumatology. 12(11), 625-626.
- (2016). Suppressive activity of human regulatory T cells is maintained in the presence of TNF. NATURE MEDICINE. 22(1), 16-+.
Research Areas:
Research & Experimental Medicine,
Engineering,
Science & Technology - Other Topics,
Oncology,
Biochemistry & Molecular Biology,
Materials Science,
Biophysics,
Pharmacology & Pharmacy,
Infectious Diseases,
Cell Biology,
Chemistry,
Hematology,
Life Sciences & Biomedicine - Other Topics,
Immunology
Research Areas: