Adelman, Karen, Ph.D.
individual record
Investigator
Positions:
- Investigator, Epigenetics & Stem Cell Biology Laboratory / Transcriptional Responses to the Environment Group
overview
Karen L. Adelman, Ph.D., leads the Transcriptional Responses to the Environment Group within the Laboratory of Molecular Carcinogenesis. She earned her Ph.D. in 1999 at Universite de Paris VI, working at the Institut Pasteur. She was a postdoctoral fellow in the laboratory of John Lis, Ph.D., at Cornell University before joining NIEHS in 2005. Dr. Adelman has received a number of honors and awards during her tenure at NIEHS, including the Early Career Award in 2006 and the NIH Director's Award in 2010. She has published more than 35 articles and reviews in leading biomedical journals during her career, including more than 20 since she joined the NIEHS.
selected publications
Academic Articles56
- (2020). Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination. MOLECULAR CELL. 80(2), 345-+.
- (2020). MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation. MOLECULAR AND CELLULAR BIOLOGY. 40(11),
- (2020). RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. NATURE CELL BIOLOGY. 22(4),
- (2019). NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region. Nature Communications. 10,
- (2019). Negative elongation factor is essential for endometrial function. FASEB JOURNAL. 33(2), 3010-3023.