- Senior Investigator, Receptor Biology Section
Dr. Roche received her B.S. from Duke University. In 1995 she received her Ph.D. from Johns Hopkins University, where she worked with Richard Huganir studying the regulation of glutamate receptors. She then did a postdoctoral fellowship with Robert Wenthold in the NIDCD, where she investigated the cell biology of glutamate receptor transport and localization. Dr. Roche joined NINDS as an Investigator in 2001. The main focus of her laboratory is the study of neurotransmitter receptor expression and targeting to the synapse.
- (2020). Neuroligins and Neurodevelopmental Disorders: X-Linked Genetics. Frontiers in Synaptic Neuroscience. 12,
- (2020). Kalirin and Trio: RhoGEFs in Synaptic Transmission, Plasticity, and Complex Brain Disorders. TRENDS IN NEUROSCIENCES. 43(7), 505-518.
- (2020). Regulation of NMDA glutamate receptor functions by the GluN2 subunits. JOURNAL OF NEUROCHEMISTRY. 154(2), 121-143.
- (2020). A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y. NEURON. 106(5), 759-+.