- Investigator, Unit on Genetics of Cognition and Behavior in the Mood and Anxiety Disorder Program
Dr. Nakazawa is chief of the Unit on Genetics of Cognition and Behavior in the Mood and Anxiety Disorder Program, National Institute of Mental Health, National Institutes of Health. Dr. Nakazawa received his Ph.D. from Keio University School of Medicine in Tokyo, Japan, investigating the elucidation of molecular diversity of glycosyltransferase families. In 1991, he began post-doctoral training in neuroscience at the Laboratory for Neural Networks, Frontier Research Programs (later joined with the Brain Science Institute) in the RIKEN Institute at Wako, Japan. During this time, his research focused on the molecular and cellular mechanisms of cerebellar long-term depression. In 1995 he moved to the Center for Learning and Memory at Massachusetts Institute of Technology (MIT) as a research fellow, and he became a research associate in 2000. While at MIT, Dr. Nakazawa developed cell type-restricted gene manipulation system in hippocampal CA3 by over-expressing Cre recombinase in transgenic mice.
- (2010). Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. NATURE NEUROSCIENCE. 13(1), 76-U240.
- (2010). eIF2 alpha Phosphorylation-Dependent Translation in CA1 Pyramidal Cells Impairs Hippocampal Memory Consolidation without Affecting General Translation. JOURNAL OF NEUROSCIENCE. 30(7), 2582-2594.
- (2009). Lack of kainic acid-induced gamma oscillations predicts subsequent CA1 excitotoxic cell death. EUROPEAN JOURNAL OF NEUROSCIENCE. 30(6), 1036-1055.
- (2006). Inducible and cell-type restricted manipulation in the entorhinal cortex. NEURON. 50(2), 183-185.