Scholars

Gottesman, Michael M., M.D.

Senior Investigator

Positions:

Senior Investigator, Laboratory of Cell Biology

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Dr. Gottesman obtained his M.D. from Harvard University Medical School, completed his internship and residency in medicine at the Peter Bent Brigham Hospital in Boston, and received his postdoctoral research training in molecular genetics with Martin Gellert at the NIH. After a year as an assistant professor in the Department of Anatomy at Harvard, he moved to the NIH in 1976. He currently serves as the NIH deputy director for intramural research as well as chief of the Laboratory of Cell Biology.

selected publications

Articles1

(1981). INVITRO ASSEMBLY OF HOMOPOLYMER AND CO-POLYMER FILAMENTS FROM INTERMEDIATE FILAMENT SUBUNITS OF MUSCLE AND FIBROBLASTIC CELLS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 78(6), 3692-3696.

Academic Articles500

(2020). Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer. 21(11),
(2020). Inhibition of glutathione peroxidase mediates the collateral sensitivity of multidrug-resistant cells to tiopronin (vol 289, pg 21473, 2014). JOURNAL OF BIOLOGICAL CHEMISTRY. 295(13), 4370-4370.
(2020). A role for ceramide glycosylation in resistance to oxaliplatin in colorectal cancer. EXPERIMENTAL CELL RESEARCH. 388(2),
(2020). Collateral Sensitivity of Multidrug-Resistant Cells to the Orphan Drug Tiopronin (Retraction of Vol 54, Pg 4987, 2011). JOURNAL OF MEDICINAL CHEMISTRY. 63(3), 1443-1443.
(2020). Mycoplasma Infection Mediates Sensitivity of Multidrug-Resistant Cell Lines to Tiopronin: A Cautionary Tale. JOURNAL OF MEDICINAL CHEMISTRY. 63(3), 1434-1439.

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Articles1

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