Scholars

Gottesman, Michael M., M.D.

Senior Investigator

Positions:

Senior Investigator, Laboratory of Cell Biology

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overview

Dr. Gottesman obtained his M.D. from Harvard University Medical School, completed his internship and residency in medicine at the Peter Bent Brigham Hospital in Boston, and received his postdoctoral research training in molecular genetics with Martin Gellert at the NIH. After a year as an assistant professor in the Department of Anatomy at Harvard, he moved to the NIH in 1976. He currently serves as the NIH deputy director for intramural research as well as chief of the Laboratory of Cell Biology.

selected publications

Articles1

(1981). INVITRO ASSEMBLY OF HOMOPOLYMER AND CO-POLYMER FILAMENTS FROM INTERMEDIATE FILAMENT SUBUNITS OF MUSCLE AND FIBROBLASTIC CELLS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 78(6), 3692-3696.

Academic Articles500

(2016). Basic science: Bedrock of progress. SCIENCE. 351(6280), 1405-1405.
(2016). Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier. Scientific Reports. 6,
(2016). Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras. 7(43), 69804-69815.
(2016). Cryo-EM Analysis of the Conformational Landscape of Human P-glycoprotein (ABCB1) During its Catalytic Cycle. MOLECULAR PHARMACOLOGY. 90(1), 35-41.
(2016). F-18-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier. NEUROIMAGE. 138, 134-140.

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Articles1

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