Eichacker, Peter Q., M.D.
individual record
Senior Investigator
Positions:
- Senior Investigator, Critical Care Medicine Department
Research Areas:
Food Science & Technology,
General & Internal Medicine,
Endocrinology & Metabolism,
Anesthesiology,
Biochemistry & Molecular Biology,
Cardiovascular System & Cardiology,
Pharmacology & Pharmacy,
Infectious Diseases,
Respiratory System,
Microbiology,
Physiology,
Immunology,
Toxicology
Research Areas:
overview
Dr. Eichacker is a Senior Investigator and Head of the Critical Care Medicine Section in the NIH Clinical Center's Critical Care Medicine Department (CCMD). He earned his undergraduate degree from Boston University and his medical degree from New York University. After he completed a residency and chief residency in internal medicine, he had a fellowship in pulmonary medicine at Bronx Municipal Hospital Center and Hospital of the Albert Einstein College of Medicine in New York. He joined NIH in 1986 as a CCMD fellow. In 1990 he was appointed Senior Investigator and Head of the Critical Care Medicine section in CCMD.
selected publications
Academic Articles147
- (2020). Inhibitory Immune Checkpoint Molecule Expression in Clinical Sepsis Studies: A Systematic Review. CRITICAL CARE MEDICINE. 48(9), 1365-1374.
- (2020). Sepsis Bundles That Focus on Clinician Judgment and Proven Interventions Are Needed to Increase Bundle Compliance and Effectiveness. CRITICAL CARE MEDICINE. 48(4), 602-605.
- (2020). The Effects of Obesity on Outcome in Preclinical Animal Models of Infection and Sepsis: A Systematic Review and Meta-Analysis. Journal of Obesity. 2020,
- (2020). Checkpoint inhibitor therapy in preclinical sepsis models: a systematic review and meta-analysis. Intensive Care Medicine Experimental. 8(1),
- (2020). Driving blind: instituting SEP-1 without high quality outcomes data. Journal of Thoracic Disease. 12, S22-S36.
- (2019). Bacillus anthracis lethal toxin, but not edema toxin, increases pulmonary artery pressure and permeability in isolated perfused rat lungs. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 316(5), H1076-H1090.
- (2019). Does Obesity Protect Against Death in Sepsis? A Retrospective Cohort Study of 55,038 Adult Patients. CRITICAL CARE MEDICINE. 47(5), 643-650.
- (2018). Evidence Underpinning the Centers for Medicare & Medicaid Services' Severe Sepsis and Septic Shock Management Bundle (SEP-1) A Systematic Review. ANNALS OF INTERNAL MEDICINE. 168(8), 558-+.
- (2018). Evidence Underpinning the Centers for Medicare & Medicaid Services' Severe Sepsis and Septic Shock Management Bundle (SEP-1) RESPONSE. ANNALS OF INTERNAL MEDICINE. 168(8), 610-612.
- (2018). Risks of restrictive red blood cell transfusion strategies in patients with cardiovascular disease (CVD): a meta-analysis. TRANSFUSION MEDICINE. 28(5), 335-345.
- (2017). Analysis of Anthrax Immune Globulin Intravenous with Antimicrobial Treatment in Injection Drug Users, Scotland, 2009-2010. EMERGING INFECTIOUS DISEASES. 23(1), 56-65.
- (2017). Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support. Intensive Care Medicine Experimental. 5,
- (2017). Bacillus anthracis Edema Toxin Increases Fractional Free Water and Sodium Reabsorption in an Isolated Perfused Rat Kidney Model. INFECTION AND IMMUNITY. 85(7),
- (2017). Shock and lethality with anthrax edema toxin in rats are associated with reduced arterial responsiveness to phenylephrine and are reversed with adefovir. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 313(5), H946-H958.
- (2016). Nitric oxide production contributes to Bacillus anthracis edema toxin-associated arterial hypotension and lethality: ex vivo and in vivo studies in the rat. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 311(3), H781-H793.
- (2015). An overview of investigational toxin-directed therapies for the adjunctive management of Bacillus anthracis infection and sepsis. EXPERT OPINION ON INVESTIGATIONAL DRUGS. 24(7), 851-865.
- (2015). Bacillus anthracis edema but not lethal toxin challenge in rats is associated with depressed myocardial function in hearts isolated and tested in a Langendorff system. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 308(12), H1592-H1602.
- (2015). Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies. Toxins. 7(12), 5417-5434.
- (2014). Confirmed Bacillus anthracis Infection among Persons Who Inject Drugs, Scotland, 2009-2010. EMERGING INFECTIOUS DISEASES. 20(9), 1452-1463.
- (2014). Hypothalamic-pituitary-adrenal axis in lethal canine Staphylococcus aureus pneumonia. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 307(11), E994-E1008.
Research Areas:
Food Science & Technology,
General & Internal Medicine,
Endocrinology & Metabolism,
Anesthesiology,
Biochemistry & Molecular Biology,
Cardiovascular System & Cardiology,
Pharmacology & Pharmacy,
Infectious Diseases,
Respiratory System,
Microbiology,
Physiology,
Immunology,
Toxicology
Research Areas: