- Stadtman Investigator, Gene Regulation and Chromosome Biology Laboratory
Shuo Gu received his B.A. in Tsinghua University, CHINA in 1998. He completed his Ph.D. training in the laboratory of Dr. John Rossi at Beckman Research Institute, City of Hope, Los Angeles. Shuo Gu undertook his postdoctoral training in the laboratory of Dr. Mark Kay at Stanford University Medical School, Palo Alto. Both his Ph.D. and postdoctoral research focused on the mechanisms of RNA interference and microRNA pathways, and their applications in gene therapy. He Joined the Gene Regulation and Chromosome Biology Laboratory in 2013.
- (2020). Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells. RNA Biology. 17(11), 1603-1612.
- (2019). KSHV RNA-binding protein ORF57 inhibits P-body formation to promote viral multiplication by interaction with Ago2 and GW182. NUCLEIC ACIDS RESEARCH. 47(17), 9368-9385.
- (2016). Cytoplasmic Drosha activity generated by alternative splicing. NUCLEIC ACIDS RESEARCH. 44(21), 10454-10466.
- (2012). Expression determinants of mammalian argonaute proteins in mediating gene silencing. NUCLEIC ACIDS RESEARCH. 40(8), 3704-3713.