- Senior Investigator, Laboratory of Muscle Stem Cells and Gene Regulation
Dr. Sartorelli obtained his degree in Medicine from the University of Brescia, Italy and did a Residency in Oncology at the University of Milan, Italy. He joined the Genetics Department and the Department of Medicine of the Stanford University for his postdoctoral education.
In 1990, Dr.Sartorelli was appointed Assistant Professor in the Department of Chemistry at the University of Brescia, School of Medicine. In 1993, he joined the Department of Biochemistry and Molecular Biology of the Keck School of Medicine, University of Southern California as an Assistant Professor and was recruited in 1999 at the National Institutes of Health to head the Muscle Gene Expression Group within the Laboratory of Muscle Biology of the Intramural Program at the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
Academic Articles92
- (2020). Enhancer RNAs are an important regulatory layer of the epigenome. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 27(6), 521-528.
- (2019). Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions. DEVELOPMENT. 146(12),
- (2019). miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8(+) T cell fate. Nature Communications. 10,
- (2018). A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans. MOLECULAR CELL. 71(1), 129-+.
- (2018). ATP Citrate Lyase: A New Player Linking Skeletal Muscle Metabolism and Epigenetics. TRENDS IN ENDOCRINOLOGY AND METABOLISM. 29(4), 202-204.
- (2018). Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells. MOLECULAR CELL. 71(6), 1040-+.
- (2018). Identification of Skeletal Muscle Satellite Cells by Immunofluorescence with Pax7 and Laminin Antibodies. Jove-Journal of Visualized Experiments. (134),
- (2018). Shaping Gene Expression by Landscaping Chromatin Architecture: Lessons from a Master. MOLECULAR CELL. 71(3), 375-388.
- (2017). Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival. Nature Communications. 8,