- Senior Investigator, Laboratory of Muscle Stem Cells and Gene Regulation
Dr. Sartorelli obtained his degree in Medicine from the University of Brescia, Italy and did a Residency in Oncology at the University of Milan, Italy. He joined the Genetics Department and the Department of Medicine of the Stanford University for his postdoctoral education.
In 1990, Dr.Sartorelli was appointed Assistant Professor in the Department of Chemistry at the University of Brescia, School of Medicine. In 1993, he joined the Department of Biochemistry and Molecular Biology of the Keck School of Medicine, University of Southern California as an Assistant Professor and was recruited in 1999 at the National Institutes of Health to head the Muscle Gene Expression Group within the Laboratory of Muscle Biology of the Intramural Program at the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
- (2016). The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1. Cell Reports. 14(5), 1156-1168.
- (2015). EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion. Scientific Reports. 5,
- (2015). IL-6 Blockade as a Therapeutic Approach for Duchenne Muscular Dystrophy. EBioMedicine. 2(4), 274-275.
- (2015). Metabolic Reprogramming of Stem Cell Epigenetics. Cell Stem Cell. 17(6), 651-662.
- (2015). Super-enhancers delineate disease-associated regulatory nodes in T cells. NATURE. 520(7548), 558-+.